Thursday, November 15, 2012

Genetic Connections To Alzheimer's Becoming More Visible

The New England Journal of Medicine published study TREM2 Varients In Alzheimer's Disease recently.  This study strengthens the correlation between brain inflammation and an increased risk of Alzheimer's disease.

This is important now that data indicates Alzheimer's disease effects approximately 5.4 million Americans.  The undesired symptom of Alzheimer's disease being the short term memory loss. 

Genetic mutation  R47H is a variant that reduces the white blood cells ability to get rid of plaque forming protein (beta amyloid) present on cells with the bodies inflammatory response.  This plaque has residence in the Alzheimer's disease manifestation of symptoms. 

To add to the confusion not all that have the R47H genetic mutation variant will develop Alzheimer's disease.  The more researchers can comprehend about the mechanisms that contribute to Alzheimer's disease, the better Science's chances of developing effective treatment.

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