Tuesday, July 29, 2014

Ebola Attacks The Vascular System

Ebola is a (Filoviridae) virus that appears like a long tube with a looped end under magnification.  Ebola is spread by contact transmission.  The precise natural reservoir is unknown.  Ebola progresses rapidly in humans which can result in some incidences of the actual diagnosis occurring after death.

First signs can include fever, headache, general pain, feeling tired.  Initial signs resemble the symptoms that manifest with many different bugs looking much like a case of flu.  Focus of the viral process is connected to the liver and the blood vessel endothelium.  Components of Ebola seem to attach to macrophage which then disrupt the lining of the blood vessels. 

Disrupting the integrity of the blood vessels allows fluid (blood) carrying much needed oxygen and cell nutrients to leak out.  This progresses to internal and external bleeding causing organs to lose oxygen and nutrients and fail.

Early on lab test antigen- capture ELISA can detect the presence of antigen.  Treatment involves quarantine and management of symptoms.  Currently each diagnosis of the Ebola virus is applied as a predictive application for the manifestation of the risk.  This is tracking with comprehensive interventions to contain the virus and prevent further spread.

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