Vemurafenib performed well as PLX4032 in recent clinical trial. Vemurafenib is an investigational medication that can be taken by the mouth.
Melanoma is skin cancer. Skin cancer becomes deadliest when it spreads to other parts of the body. Researchers for Roche a research focused biotech company located in Basel Switzerland are looking for ways to stop the ability of the cancer to grow and spread.
BRAF protein is a protein involved in sending signals to cells with cell growth. In cases where cancer is being spread by the help of BRAF protein, Vemurafenib acts to inhibit BRAF protein signals, and stop growth. Use of Vemurafenib to stop the cancer causing mutated form of BRAF protein led to significant tumor shrinkage. This translates to reduced risk of disease worsening, a progression free survival.
A Roche Genentech developed product, Vemurafenib has a safety profile consistent with previous clinical studies. Expect this drug to apply for market approval with the FDA.
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