Dimebon Home Care Path

Dimebon (Latrepirdine, Dimebolin) is an antihistamine drug. A 1980's Russian drug sold over the counter for hayfever symtpoms. Recently recognized by the pharmaceutical industry for its neuro protective properties, with a potential to combat Alzheimer's disease. Dimebon has been shown to inhibit brain cell death in pre clinical studies of Alzheimer's disease. The earliest series of studies were able to show the results necessary to facilitate the continuation of clinical research trials. In April of 2009 Pfizer and Medivation announced trials were unable to show desired benefit to participants with symptoms of Alzheimer's disease. This has been frustrating for prescribers who saw early trials of Dimebon demonstrate an ability to inhibit cellular death associated with neuro degenerative diseases. Currently The Dean Foundation www.dean.org is conducting a clinical research study to test the effects of an investigational medication (Dimebon) in patients with Alzheimer's disease . The study is to determine if Dimebon improves cognition, memory, daily functioning, caring for oneself, and behavior over a 12 month period. Participants will be required to have a regular care giver attend all 10 visits over the 12 month period. Home Care Path www.homecarepath.com staff attend provider visits with seniors to help improve follow through in the home setting. This Dean study is number 549, and JoAnn in Madison Wisconsin is the contact person.